Principally set in Egypt, near the end of the Ptolemaic period from 49 to 38 BC, the story follows a Medjay named Bayek of Siwa and his wife Aya as they seek revenge for the murder of their son. It also explores the origins of the Assassin Brotherhood—referred here to as the Hidden Ones—and of their millennia-long conflict with the Order of the Ancients—forerunners to the Templar Order.